World Coronavirus Disease 2019 (COVID.19) is infected with the pandemic disease, 1,2 and New York City has emerged as the epicentre. Here, we identify 393 consecutive patients with Quad 19 who were admitted to two New York City hospitals.
This previous case series includes certified 19 adults aged 18 and older with a quadrilateral referral centre comprising 862 beds between March 5 and March 27, 2020, and About 180 people were admitted. Non-teaching Community Hospital in Manhattan. Both hospitals adopted the initial entrapment strategy during this time, with limited use of the high-flow nasal canal. The cases were confirmed by reverse transcriptase-polymerase chain-reaction assays performed on nasopharyngeal swab specimens. Data were manually summarized by electronic health records using the Quality Controlled Protocol and the Structured Abstraction Tool.
In 393 patients, the average age was 62.2 years, 60.6% were male, and 35.8% were obese (Table 1). The most common symptoms are cough (.4.44%), fever (.1 77..1%), dyspnea (.5. 56%), myalgias (२.8..8%), diarrhoea (%. .7.7%), and nausea and vomiting (19.1%) (Table S1 in the Supplement). Annexure). Most patients (90.0%) had lymphopenia, 27% had thrombocytopenia, and many patients had signs of liver function and inflammation. Between March 5 and April 10, respiratory failure led to invasive mechanical ventilation in 130 patients (33.1%). To date, only 43 of these patients (33.1%) have been excluded. In total, 40 patients (10.2%) have died, and 260 (66.2%) have been discharged from the hospital. Outcome data is incomplete for the remaining 93 patients (23.7%). Patients with invasive mechanical ventilation are more likely to be menopausal, obese, and have liver function values and inflammatory markers (ferritin, D-dimer, C-reactive protein, and proclisitone). Invasive Mechanical Ventilation Of the patients receiving invasive mechanical ventilation, 40 (30.8%) did not require additional oxygen during the first 3 hours after being presented to the emergency department. Patients receiving invasive mechanical ventilation require vasopressor support (95.4% vs 1.5%) and have other complications, including atrial arrhythmias (17.7% vs. 1.9%) and new kidney replacement therapy (13.3% vs 0.4%). 3). Of the 393 patients with CoD-19 who were admitted to two New York City hospitals, the prevalence of these diseases was generally similar to that in a large case series from China 1. However, gastrointestinal symptoms appear to be more common than in China (where they occur in 4 to 5 percent of patients). This difference may reflect geographical variation or discrimination reporting. Obesity was common and could be a risk factor for respiratory failure that results in invasive mechanical ventilation. This difference may reflect geographical variation or discrimination reporting. Obesity was common and could be a risk factor for respiratory failure that results in invasive mechanical ventilation. The number of patients in our case series was more than 10 times that in China; Possible contributors include the more severe illness we have (since testing and hospitalization in the United States is limited to most disease patients) And our hospitals use an early intubation strategy. At the Pole View, the high-demand hospital for invasive mechanical ventilation is living a life of overwhelming resources. Deviation In many patients the condition was stable before air. Invasive mechanical ventilation presents almost a festival in patients with no extra oxygen required at this time. Observations that patients who received almost universally aggressive mechanical ventilation sought support for vasopressor and many received new kidney replacement therapy, which suggests that these resources are stored. There is also a need to strengthen the investment and supply chain.
Parag Goyal, M.D.
Justin J. Choi, M.D.
Laura C. Pinheiro, M.P.H., Ph.D.
Edward J. Schenck, M.D.
Ruijun Chen, M.D.
Assem Jabri, M.D.
Michael J. Satlin, M.D.
Thomas R. Campion, Jr., Ph.D.
Musarrat Nahid, M.Sc.
Joanna B. Ringel, M.P.H.
Katherine L. Hoffman, M.S.
Mark N. Alshak, B.A.
Han A. Li, B.A.
Graham T. Wehmeyer, B.S.
Mangala Rajan, M.B.A.
Evgeniya Reshetnyak, Ph.D.
Nathaniel Hupert, M.D., M.P.H.
Evelyn M. Horn, M.D.
Fernando J. Martinez, M.D.
Roy M. Gulick, M.D., M.P.H.
Monika M. Safford, M.D.
Weill Cornell Medicine, New York, NY
pag9051@med.cornell.edu
New York - Supporting Presbyterian Hospital and Well Colonel Medicine, including the Clinical and Translational Science Center (with a grant from the National Institutes of Health [UL1 TR000457]) and the joint clinical trials office of Well Colonel Medicine.

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